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Senior Transnational Scientist

Job Field:
Clinical Research Jobs
Clinical Pharmacology Jobs
Switzerland All
Contract Type:
118,000 to 135,000 per annum
Key People
Job Ref:

An excellent opportunity has arisen to join a leading pharmaceutical company as a Senior Translational Scientist.

Our clients Pharmacology & Screening team is dedicated to accelerating the development of new therapies for cancer by leveraging the knowledge around our drug candidates.
Your main responsibilities:

*Works in matrix organization in close collaboration with other Translational Medicine functions (DMPK, Preclinical Safety and Diagnostics/Personalized Medicine) to characterize the pharmacological properties of our drug candidates:
*Represents the Translational Pharmacology function in the Translational Medicine Project Teams;
*May represent the Translational Medicine function in the global Project Teams and lead a Translational Medicine Project Team (core team member).
*Manages laboratory-to-human research in Contract Research Organizations: designs, monitors, and reports the primary and secondary pharmacology studies performed:
*In vitro/in vivo pharmacology compounds selection and profiling, including off target characterization
*Proof of concept in vivo studies - PK/PD
*Mechanism of action studies
*Identification, method development/validation of clinical pharmacodynamic (PDy) biomarkers
*As clinical study team member
*Defines and manages the clinical translational PDy analyses (incl. blood and tissue biomarkers), data analyses and reporting according to GCPs and GCLPs
*Supports and advises the Clinical Research and Development team
*Contributes to the preparation of the pharmacology regulatory documentation (IDB, summaries for IND and IMPD, briefing documentation)
*May participate in interactions with Health Authorities.
*Participates in external scientific communications (publications, poster and oral presentations).
Your profile:
*PhD in relevant expertise area or equivalent in biomedical engineering
*More than 5 years demonstrated experience in Translational Pharmacology Research and drug development in oncology projects
*Experience in the pharma industry a strong asset
*In-depth knowledge in translational research in personalized oncology and basic knowledge of related disciplines including histopathology, bioanalytics, pharmacokinetics and PK/PD
*Knowledge of GCP, GCLP and ICH guidelines; animal welfare regulations; and cancer drug development and regulations
*Very good IT and analytical skills incl. advanced graphical explorations (R statistical software and image analysis, a plus)
*Excellent communication and presentation skills (oral and written)
*Fluent in English
*Project management experience
*Excellent team working skills
*Ability to influence through the matrix, demonstrated assertiveness and impact in communication

Please contact Mark Cussens, Clinical Research Recruiter on
Tel: +44 1727 817623 or email:
Tel: +41 4350 86620 or email:

Key People is a recruitment company with a reputation for providing good value that's been built up over 20 years.
-We achieve results faster
-Our candidates really are a cut above
-We add greater value
We think it's because we're a private company driven by clients, not by shareholders.

For our candidates, we have developed relationships with thousands of clients nationwide and across Europe, who choose to recruit through Key People, so you'll have a wide choice of opportunities to further your career.

Closing Date:

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